React Health G3 X APAP Machine with Cellular Modem & Heated Tubing
React Health's foam-free G3 X APAP machine comes equipped with an integrated humidification system, heated tubing, React Health's proven algorithim, and a 4G cellular modem to provide seamless care management through the React Health Connect cloud platform.



React Health G3 X APAP Machine with Cellular Modem & Heated Tubing Overview
The G3 X APAP Machine by React Health is designed to eliminate foam‑related safety risks and concerns found in many PAP devices. Their five‑year warranty provides long‑term support and reliability for your sleep apnea therapy journey. Featuring a proven algorithm for effective sleep therapy, SMART technology that conforms to your specific needs, and seamless care management through the React Health Connect integrated cloud platform.
Smart A Custom Pressure Response for Precision Care
React Health's Smart A technology fine-tunes the Auto Algorithm of the G3 X device to respond to your specific pressure needs to provide comfort and success with your PAP therapy.
The Smart A algorithm uses data from a rolling 5-effective treatment sessions. An effective treatment session is defined as at least 4 hours of use and a controlled leak (<90 lpm). The algorithm looks at the 50th and 95th percentile to determine where Auto min and Auto max should be adjusted.
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Foam Free - The G3 X APAP Machine by React Health is the first standard-size PAP device available in the U.S. designed without any polyurethane sound-abatement foam while still providing low noise levels during operation.
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Proven Algorithm & SMART Features - Custom pressure response and SMART A continuously responds to your specific therapy needs for unparalleled comfort and effective therapy.
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Integrated Humidification & Heated Tubing - Humidifies and warms the pressurized air that is delivered to the upper airway for enhanced comfort and to help prevent side effects such as dry mouth, sore throat, and more.
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4G Cellular Modem - Equipped with a 4G cellular modem, the G3 X allows you to wirelessly transmit your therapy data to the integrated cloud platform, React Health Connect, for seamless care management.


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1 — G3 X APAP Machine
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1 — Power Adapter
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1 — Power Cord
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1 — Tubing Elbow Adapter
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1 — Heated Tubing
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1 — Reusable Air Filter
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1 — Disposable Ultrafine Filter
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1 — SD Card
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1 — Cellular Module
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1 — Carrying Case
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1 — User Manual
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CPAP/BiPAP/APAP Machine Replacement Frequency: Resupply Every 5 Years
- Disposable Filters Replacement Frequency: Resupply Every 2 Weeks
- Reusable Filters Replacement Frequency: Resupply Every 6 Months
- Tubing Replacement Frequency: Resupply Every 3 Months
- Water Chamber Replacement Frequency: Resupply Every 6 Months
| Brand | React Health |
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| Weight | 3.74 lbs |
| SKU | 29129 |
| Model | G4600 |
| HCPCS | E0601 |
| Prescription Required | Yes |
| Manufacturer's Warranty | 5-year limited manufacturer's warranty |
| FSA/HSA Eligible | Yes |
| Dimensions | 10.43" (L) x 5.7" (W) x 4.49" (H) |


























